| Date | Home | Away | Result |
|---|---|---|---|
| 2/21/25 1:30 PM | Sampdoria Genua | Sassuolo Calcio | 0-0 |
| 2/22/25 8:00 AM | AS Cittadella | Modena FC | --- |
| 2/22/25 8:00 AM | AC Reggiana 1919 | Carrarese Calcio 1908 | --- |
| 2/22/25 8:00 AM | AC Pisa | Juve Stabia | --- |
| 2/22/25 8:00 AM | Mantova 1911 | SSC Bari | --- |
| 2/22/25 10:15 AM | US Cremonese | FC Cesena | --- |
| 2/23/25 8:00 AM | Brescia Calcio | FC Südtirol | --- |
| 2/23/25 8:00 AM | Cosenza Calcio | Palermo FC | --- |
| 2/23/25 8:00 AM | Spezia Calcio | US Catanzaro 1929 | --- |
| 2/23/25 10:15 AM | US Salernitana | Frosinone Calcio | --- |